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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CIR1
All Species:
12.73
Human Site:
S359
Identified Species:
25.45
UniProt:
Q86X95
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X95
NP_004873.3
450
52313
S359
H
S
D
S
D
K
K
S
R
T
H
K
H
S
P
Chimpanzee
Pan troglodytes
XP_001148591
450
52340
S359
H
S
D
S
D
K
K
S
R
T
H
K
H
S
P
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535968
475
55209
S366
H
S
D
S
D
R
K
S
R
S
H
N
Q
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9DA19
450
51819
E360
P
K
Q
E
S
S
G
E
N
S
M
W
V
H
S
Rat
Rattus norvegicus
Q5U2T8
451
51398
S358
L
R
L
L
K
Q
E
S
S
G
E
N
S
T
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514863
861
95412
S366
Y
S
G
S
D
R
K
S
K
R
R
N
Q
S
P
Chicken
Gallus gallus
Q5ZI03
460
53359
G353
S
K
R
S
S
C
E
G
E
R
K
S
K
S
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689017
177
20337
G87
K
E
E
T
K
E
G
G
E
S
E
Y
K
F
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649072
366
43629
K276
K
K
K
S
K
K
D
K
S
S
R
K
D
K
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_491654
560
65813
Q432
S
S
I
R
K
E
S
Q
R
V
R
K
H
S
P
Sea Urchin
Strong. purpuratus
XP_794696
488
58217
D392
S
P
S
H
G
R
H
D
R
N
G
K
D
R
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8VZ67
595
69129
D435
D
R
P
S
A
S
S
D
D
S
D
Y
Y
R
S
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
N.A.
84
N.A.
80.2
80.2
N.A.
43.5
70
N.A.
33.3
N.A.
38.4
N.A.
36.4
41.3
Protein Similarity:
100
99.5
N.A.
89.4
N.A.
86
86.6
N.A.
48.3
81.5
N.A.
36.6
N.A.
52.4
N.A.
51.2
56.5
P-Site Identity:
100
100
N.A.
73.3
N.A.
0
6.6
N.A.
46.6
13.3
N.A.
0
N.A.
20
N.A.
40
13.3
P-Site Similarity:
100
100
N.A.
86.6
N.A.
6.6
26.6
N.A.
66.6
20
N.A.
26.6
N.A.
26.6
N.A.
46.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
25
0
34
0
9
17
9
0
9
0
17
0
0
% D
% Glu:
0
9
9
9
0
17
17
9
17
0
17
0
0
0
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
9
0
9
0
17
17
0
9
9
0
0
0
0
% G
% His:
25
0
0
9
0
0
9
0
0
0
25
0
25
9
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
25
9
0
34
25
34
9
9
0
9
42
17
9
9
% K
% Leu:
9
0
9
9
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
9
0
25
0
0
0
% N
% Pro:
9
9
9
0
0
0
0
0
0
0
0
0
0
0
42
% P
% Gln:
0
0
9
0
0
9
0
9
0
0
0
0
17
0
9
% Q
% Arg:
0
17
9
9
0
25
0
0
42
17
25
0
0
17
9
% R
% Ser:
25
42
9
59
17
17
17
42
17
42
0
9
9
50
17
% S
% Thr:
0
0
0
9
0
0
0
0
0
17
0
0
0
9
0
% T
% Val:
0
0
0
0
0
0
0
0
0
9
0
0
9
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% W
% Tyr:
9
0
0
0
0
0
0
0
0
0
0
17
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _